Antibodies toBordetella pertussisadenylate cyclase toxin in neonatal and maternal sera

Pharmacokinetics of amoxicillin in maternal, umbilical cord, and neonatal sera.

The pharmacokinetics of amoxicillin were studied in umbilical cord and neonatal sera relative to maternal concentrations in prevention of neonatal group B streptococcus infection. The subjects were 44 pregnant women receiving amoxicillin as 1 or 2 g as an intravenous infusion. To measure the concentrations, blood samples were obtained from the mother, the arterial and venous umbilical cord, and...

Familial Neonatal Neutropenia with Maternal Leukocyte Antibodies

I SOIMMUNE leukocyte antibodies have been reported frequently since the initial communication of Dausset and Nenna’ in 1952. A large literature has accumulated and was recently fully reviewed by Walford,2 who listed over 500 reports. Most of these have been concerned chiefly with establishing the presence of such antibodies, the mechanisms by which they cause pathological effects being still co...

The Relationship between Neonatal Jaundice and Maternal and Neonatal Factors

Background: Maternal and neonatal factors could help determine the potential incidence of hyperbilirubinemia. In this study, we aimed to identify the relationship between the severity of jaundice in newborns and maternal and neonatal factors. Methods: This descriptive, cross-sectional study was conducted in 2014. Icteric newborns, admitted to Qods and Kowsar teaching hospitals in Qazvin, Iran ...

Leukocyte antibodies in human sera and in immune rabbit sera.

Maternal microbiota and antibodies as advocates of neonatal health

Mammalian body surfaces are inhabited by vast numbers of microbes, the commensal microbiota, which help the host to digest food, provide nutrients, and mature its immune system. For a long time, postnatal colonization was believed to be the main stimulus for microbial-induced immune development. Using a model of reversible colonization of germ-free mice during gestation, we recently showed that...